{"id":1774,"date":"2024-01-08T06:16:32","date_gmt":"2024-01-08T14:16:32","guid":{"rendered":"https:\/\/revitalizemetabolichealth.com\/?p=1774"},"modified":"2024-01-08T06:16:32","modified_gmt":"2024-01-08T14:16:32","slug":"nutrient-bioavailability-intro-iron","status":"publish","type":"post","link":"https:\/\/revitalizemetabolichealth.com\/nutrient-bioavailability-intro-iron\/","title":{"rendered":"Nutrient Bioavailability – Intro & Iron"},"content":{"rendered":"
Bioavailability refers to what percentage of a consumed material is absorbed into the body\u2019s bloodstream.\u00a0 In the pharmaceutical world, drug bioavailability is a critical aspect of drug design to ensure that drugs reach a particular concentration.\u00a0 There may be many factors that influence bioavailability, such as mode of administration, digestive enzyme activity, gastrointestinal motility, intestinal flora, co-administered substances, etc.\u00a0 A medication that is administered intravenously (IV) is said to have 100% bioavailability, because it is placed directly into the bloodstream. \u00a0In contrast, the bioavailability of oral penicillin V is 60% (ref<\/a>).<\/p>\n <\/p>\n Bioavailability is incredibly important in the pharmaceutical industry, because it defines the dose of the drug that is required in order to achieve the desired effect.<\/p>\n Similarly, the degree of absorption of micronutrients<\/a> from our food sources is important, because it defines how much food one must consume to reach the recommended levels.<\/p>\n Nutrients are required for proper growth and functioning of the human body.\u00a0 The condition whereby nutrients are present in unbalanced quantities in the human body and are contributing to adverse health effects is called malnutrition.\u00a0 When there are deficiencies in the micronutrient content of diets despite adequate energy intake, that condition is called hidden hunger.<\/p>\n Hidden hunger is common in developing countries, with iron and zinc being the most common micronutrient deficiencies.\u00a0 In the USA, Canada, and European countries, there are also reported deficiencies in iron, iodine, vitamin D, and vitamin E (ref<\/a>).<\/p>\n Iron is an essential element for the human body, as it participates in many critical functions.\u00a0 Iron exists in 2 forms:<\/p>\n Red meat is the predominant source of dietary iron since it is rich in heme iron, which is more bioavailable.\u00a0 Heme iron is absorbed in the human gut more efficiently (7-35%) compared to nonheme iron (2-20%) (ref<\/a>).\u00a0 The average daily iron intake in humans is 10 \u2013 15 mg, with only 1 \u2013 2 mg actually being absorbed through the intestine.<\/p>\n Even if plants have high iron content, the absorption of iron is low due to the presence of antinutrients that bind iron.\u00a0 Calcium, polyphenols, and phytates are known to decrease absorption of iron.\u00a0 Vitamin C (ascorbic acid) and protein known to enhance the absorption of iron.\u00a0 Also, adding meat to a plant meal enhances the absorption of nonheme iron (ref<\/a>).<\/p>\n Absorption rate of iron from various food sources:<\/p>\n What is Bioavailability? Bioavailability refers to what percentage of a consumed material is absorbed into the body\u2019s bloodstream.\u00a0 In the pharmaceutical world, drug bioavailability is a critical aspect of drug design to ensure that drugs reach a particular concentration.\u00a0 There may be many factors that influence bioavailability, such as mode of administration, digestive enzyme activity, gastrointestinal motility, intestinal flora, co-administered substances, etc.\u00a0 A medication that is administered intravenously (IV) is said to have 100% bioavailability, because it is placed directly into the bloodstream. \u00a0In contrast, the bioavailability of oral penicillin V is 60% (ref). Bioavailability is incredibly important in the\u2026<\/p>\n","protected":false},"author":2,"featured_media":1777,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[13],"tags":[164,29],"blocksy_meta":"","aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/revitalizemetabolichealth.com\/wp-json\/wp\/v2\/posts\/1774"}],"collection":[{"href":"https:\/\/revitalizemetabolichealth.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/revitalizemetabolichealth.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/revitalizemetabolichealth.com\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/revitalizemetabolichealth.com\/wp-json\/wp\/v2\/comments?post=1774"}],"version-history":[{"count":3,"href":"https:\/\/revitalizemetabolichealth.com\/wp-json\/wp\/v2\/posts\/1774\/revisions"}],"predecessor-version":[{"id":1779,"href":"https:\/\/revitalizemetabolichealth.com\/wp-json\/wp\/v2\/posts\/1774\/revisions\/1779"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/revitalizemetabolichealth.com\/wp-json\/wp\/v2\/media\/1777"}],"wp:attachment":[{"href":"https:\/\/revitalizemetabolichealth.com\/wp-json\/wp\/v2\/media?parent=1774"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/revitalizemetabolichealth.com\/wp-json\/wp\/v2\/categories?post=1774"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/revitalizemetabolichealth.com\/wp-json\/wp\/v2\/tags?post=1774"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}Nutrient deficiency<\/strong><\/h3>\n
Iron<\/strong><\/h4>\n
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